Xanthogranulomatous endometritis presenting as pyometra and mimicking carcinoma on imaging

Xanthogranulomatous endometritis presenting as pyometra and mimicking carcinoma on imaging

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Xanthogranulomatous endometritis (XGE) is an uncommon but well-established histopathological entity seen affecting the kidney and gallbladder.Involvement of the endometrium is very rare, with only a few case reports in world Mountaineering - Homme - Skis literature till date.Histologically, it is characterized by the replacement of the endometrium by sheets of foamy histiocytes, plasma cells, lymphocytes, giant cells, and siderophages.We present a case of a 74-year-old female who presented with foul-smelling Fryer Accessories discharge and postmenopausal bleeding of a short duration.Clinical examination and imaging studies revealed a pyometra, cervical stenosis.

A suspicion of carcinoma was raised.Since XGE may mimic an endometrial carcinoma clinically and pathologically, knowledge of this unusual and rare inflammatory pathology is important for both the gynecologists and the pathologists.